This fellowship program will emphasize clinical pharmacology related to antiretrovirals and other medications frequently used in combination with antiretrovirals. The fellow will learn essential skills for analytic methods, clinical research methods, study design and data analysis, specifically related to pharmacokinetics and pharmacodynamics. These skills will be developed primarily through hands on experience with grant submission, study conduct, data analysis, and presentation/publication of independent and consortium research projects under the direction of the fellowship director. Graduate coursework will also be available. The fellow will be expected to develop and conduct their own independent research over the 2-3 year fellowship and present those findings at a scientific meeting and in a peer reviewed publication.